Ashwanostress Ingredients

Professional Information

Scheduling status S0

• Name of medicine
• Qualitative and Quantitative Composition 

• Pharmaceutical form
  
  • White capsules.
• Clinical Particulars
  • Therapeutic Indications
    • The compounds in ASHWANOSTRESS have been shown to:
      • Reduce anxiety and nervous tension
      • Support restful sleep
      • Sharpen focus and improve memory
  • Posology and method of administration
    
    • Adults: Take one capsule daily
    • Elderly populations: No studies  have been performed in elderly populations, but no dose adjustment is expected to be required.
    • Paediatric populations: The use in children under 12 years of age has not been established due to lack of adequate data.
  • Contraindications:
    • Do not take ASHWANOSTRESS if you are allergic to any of the other ingredients.
    • If the symptoms persist longer than 2 weeks during the use of the medicinal product, a doctor or a qualified health care practitioner should be consulted.
    • If the symptions worsen during the use of the medicinal product, a doctor or a qualified health care practitioner should be consulted. 
    • Special warnings and precautions for use:
      • None Known
    • Interactions with other medicines and other forms of interaction:
      • None Known
    • Fertility, pregnancy, and lactaction:
      
      • The use of ASHWANOSTRESS during pregnancy and lactaction is not recommended.
    • Undesirable effects:
      • Common side effects are mild and include stomach upset, loose stools, nausea, and drowsiness.
    • Overdose:
      • Taking too much ASHWANOSTRESS may cause side effects such as nausea, indigestion, bloating, or diarrhoea. Taking high doses of ashwagandha has been associated with symptoms such as jaundice, pruritus, nausea, lethargy, abdominal discomfort, and hyperbilirubinemia due to liver injury.
• Pharmacological properties:
  
  • Ashwagandha: It is one of the most important herbs of India's traditional Ayurveda medicine. The biologically active chemical constituents of Withania somnifera include alkaloids (isopelletierine, anaferine, cuseohygrine, anahygrine, etc), steroidal lactones(withanolides, withaferins) and saponins. Sitoindosides and acylsterylglucosides in Ashwaganda are antistress agents.
    
    Modern studies have shown that these components do give the herbs properties which include relieving phyiscal stress as well as improved cognitive abilities in children with memory deficit and old age. It has anxiolytic effects and improves energy levels and mitochondrial health.
  • Passionflower: Traditional herbal medicinal product for relief of mild symptoms of mental stress and to aid sleep.
  • Valerian: Herbal medicinal product for the relief of mild nervous tension and sleep disorders.
  • Black Pepper: Stimulates appetite. Contains antioxidants to relieve oxidative stress.
  • Pyridoxine: Contributes to normal functioning of the nervous system. Contributes to the reduction of tiredness and fatigue. A factor in the maintenance of good health.
• Pharmaceutical properties:
  • List of excipients:
    • Corn starch
    • Magnesium stearate
    • silicone dioxide
  • Incompatibilities:
    • In the abscence of studies ASHWANOSTRESS should not be given with other medicines.
  •  Special precautions for storage:
    • Keep out of reach of children.
    • Store at or below 25* C.
  • Presentation:
    • Amber glass bottle containing 30 capsules.
• Applicant:
  • Johannes J Snyman CC
    454 Koedoesnek Street,
    Waterkloof Ridge, Pretoria
• Date of revision of the text:
  • March 2024
• References:
  • N. Singh M. Bhalla, P. de Jager and M. Gilca: An overview of ashwagandha: a Rasayana ( rejuvenator) of Ayurveda. Afr J Tradit Complement Altern Med. (2011) 8(S):208-213
  • National Institute of health: Ashwagandha: Is it helpful for stress, anxiety, or sleep? Fact sheet for health professionals. Downloaded 17/03/2024.
  • KJanda, K. Wojtkowska, K. Jakubczyk et al; Passiflora incarnata in Neuropsychiatric Disorders-A Systematic Review. Nutrients 2020, 12, 3894
  •  25 March 2014 EMA/HMPC/669740/2013 Committee on Herbal Medicinal Products (HMPC) Community herbal monograph on Passiflora incarnata L., herba
  • 02 February 2016 EMA/HMPC/150848/2015, Corr.1 Committee on Herbal Medicinal Products (HMPC) European Union herbal monograph on Valeriana officinalis L., radix
  • K.Ashokkumar et al: Phytochemistry and therapeutic potential of black pepper [Piper nigrum (L.)] essential oil and piperine: a review Clinical Phytoscience volume 7, Article number:52 (2021)
  • SAHPRA guideline 7.04_CM_SE_Health_Supplements_Mar22_v4_3